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Faculty members within UC Irvine's Division of Rheumatology are actively involved in research on autoimmune diseases, including advanced studies on lupus and rheumatoid arthritis.

Rheumatologist Dr. Sheetal Desai is collaborating with the Division of Immunology to explore epigenetic alterations in DNA in patients with systemic lupus erythematosus (SLE), a chronic autoimmune disease. The studies seek to determine whether alterations in DNA from lupus patients lead to an increase in its immunogenicity, and if so to identify the receptor and signaling mechanisms activated by their DNA.

Learn more about Dr. Desai. »