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The Division of Nephrology and Hypertension at UC Irvine School of Medicine's Department of Medicine offers multiple and diverse research activities that include clinical, translational and basic research in renal physiology, kidney disease and hypertension.

Our highly productive programs, under the guidance of nationally and internationally recognized faculty members, advance the art and science of nephrology through research and discovery.

Studies carried out in our laboratories on the university campus in Irvine have helped elucidate the molecular mechanisms of lipid disorders, oxidative stress, inflammation, protein-energy wasting, malnutrition, vitamin and mineral disorders in kidney disease, epidemiology and outcomes research, racial and ethnic disparities and hypertension and dietetics.

The pioneering research conducted by our faculty members at the VA Long Beach Healthcare System, and in collaboration with other VA nephrology centers, has contributed to the understanding of molecular mechanisms of intestinal and renal tubular transport of water-soluble vitamins in health and disease. It has also contributed to better understanding of kidney disease progression, risk factors, outcomes and patient survival. The combined research efforts by our faculty has led to hundreds of original papers, which have been published in prestigious peer-reviewed journals.

In addition to providing the highest quality care to our patients, we endeavor to stem the ever-growing epidemic of chronic kidney disease by preparing well-trained and highly competent young internists and nephrologists and scientists to prevent and treat chronic kidney disease and to lead cutting-edge research.

For more information, please email Dr. Kamyar Kalantar-Zadeh at