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About Us

The Division of Basic and Clinical Immunology at UC Irvine's School of Medicine delivers state-of-the-art diagnostic and therapeutic care to children and adults, top quality physician training and lead-edge research in allergic and immunological diseases.

The division's faculty members are nationally and internationally recognized scientists who are advancing basic, clinical and translational research. They are studying the effects of environmental toxins on the immune system, working to develop vaccines to protect against potential terrorist attacks and investigating rare immunodeficiency diseases.

The division also is home to the Jeffrey Modell Diagnostic Center for Primary Immunodeficiencies, one of only 50 clinics worldwide dedicated to the diagnosis and treatment of improperly functioning immune systems. These centers are dedicated to providing leading-edge care to children and adults with primary immunodeficiencies.

Division faculty members also are committed to training physicians and scientists for medical and research careers in immunology and allergy. We offer one of the nation's most competitive ACGME-accredited post-doctoral training program in allergy and immunology. Fellows and residents are encouraged to participate in basic, clinical or translational research with faculty mentors.

The division hosts a biennial international conference focused on a variety of progressive subjects in the fast-changing field of immunology, and also organizes a biennial international conference on immunodeficiencies in collaboration with the Foundation for Primary Immunodeficiency Diseases and the Indian Society for Primary Immunodeficiency.

Division faculty members have extensive research programs underway, which provide medical students and residents in pediatrics and internal medicine with unique learning opportunities. Programs include basic research into somatic hypermutation and class-switch recombination; apoptosis, or programmed cell death, and dendritic cell biology. Faculty members also conduct transitional research into human aging and primary immunodeficiency diseases.

It is the mission of the Division of Basic and Clinical Immunology to train the best scientists and clinicians, to recruit and train outstanding faculty and to provide the highest-quality care for our patients.

We Are Greater Together

Here at UCI Department of Medicine, we highly value diversity. Diversity is core to our ability to offer compassionate and culturally competent care in a variety of practice settings, to patients from all walks of life, addressing simple to complex healthcare needs, while working with others who embrace a broad variety of backgrounds, experience, and perspectives. We remain committed to advancing diversity, in its broadest sense, in our programs through recruitment, training, retention and mentoring. This, we believe, is vital to our ability to continue to achieve excellence in serving our richly diverse community through our discover, teach, and heal mission. If this collaborative, respectful, and inclusive approach speaks to you, I look forward to your selection of UCI Department of Medicine as your training program of choice.

-Alpesh Amin, MD, MBA, MACP, SFHM